In preclinical studies, aspirin has been shown to have both anti-inflammatory and antitumor effects in the liver through inhibition of cycloxygenase-2 and platelet-derived growth factor signaling ...

Research Description: His current research is focused on the role of bioactive lipid enzymes including cycloxygenase and lipoxygenase in the growth and metastasis of lung and oesophageal cancer. Dr.

Celecoxib belongs to a class of drugs called the Coxibs, which work by inhibiting the enzyme cycloxygenase-2 (COX-2). This enzyme is key to the production of prostanglandin, an important mediator ...

Celecoxib exerts its pain relieving effects by inhibiting the enzyme cycloxygenase-2 (COX-2). This inhibition of COX-2 has been shown to cause several adverse heart effects, which has prevented ...

Figure 1 The MM BM microenvironment. On one hand, innate and adaptive immune cells are able to recognize myeloma plasma cells (PC) and generate a weak immune response against tumor. Mature dendritic ...

Isolation of lymphocytes Mice were dissected after four-week treatments. The rats’ spleens were isolated and crushed clockwise in PBS. Lymphocyte homogenates were moved into a new propylene tube, 10 ...

His current research is focused on the role of bioactive lipid enzymes including cycloxygenase and lipoxygenase in the growth and metastasis of lung and oesophageal cancer. Dr. Graham Pidgeon's group ...

Presenters noted that this was an important but unusual trial, because it examined drugs not in isolation but how they are used in combination. At the 2016 American Heart Association Scientific ...

Introduction: Bone marrow derived allogeneic mesenchymal stem cells (MSCs) from young healthy donors are immunoprivileged and are considered to be excellent cell type for cardiac regeneration. The ...

Eugenol inhibits the action of enzyme cycloxygenase (COX), which causes inflammation, making it an important remedy for inflammatory health conditions like rheumatoid arthritis, osteoarthritis and ...