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The adaptation of malignancy to therapy presents a significant challenge in cancer treatment. The cell cycle plays a crucial role in regulating the evolution of radio- and chemo-resistance in tumor ...

Reporter probes meant to track cell activity might not be as accurate as once thought. Here, melanoma cells express the extracellular signal-regulated kinase (ERK) translocation reporter. Cells ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neural stem cells (NSCs) can give rise to both ...

The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death–inducing action, we hypothesized that flavopiridol ...