Research shows polystyrene nanoplastics accelerate ovarian cancer growth by activating CDK4/6 pathways, with Palbociclib ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

Endocrine therapy is generally recommended for patients with HR+/HER2-metastatic breast cancer, with the exception of those ...

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Cyclin-dependent kinase (CDK)4/6 inhibitors are approved for the treatment of breast cancer, and they have more recently been used in patients with well ...

Background. Mammalian cardiomyocytes (CM) have limited proliferation potential, and acutely injured mammalian hearts do not regenerate adequately. Indeed, mouse CM stop proliferating rapidly after ...

This important chronobiological study in mice suggests that light modulated activity of Cdk5 activity on the PKA-CaMK-CREB signaling pathway provides missing molecular mechanistic details to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neural stem cells (NSCs) can give rise to both ...