DelveInsight's "EMPAVELI Market Size, Forecast, and Market Insight Report" highlights the details around EMPAVELI, a ...

The complement cascade is a biochemical process in the blood that helps or 'complements' cells of the immune system to eliminate invading pathogens. When activated by one of three pathways ...

Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and ...

By silencing C3, investigational ARO-C3 has the potential to treat complement-mediated renal diseases by modulating the activation of the complement cascade. Also Read: Veren Soars On Whitecap ...

EMPAVELI's unique mechanism of targeting C3 broadens its applicability beyond PNH, including other complement-driven diseases like geographic atrophy and immune complex-mediated diseases. With ...

ARO-C3 showed a maximum mean C3 reduction of 89% and sustained reduction over 87% through 24 weeks in a Phase 1/2 study. The therapy reduced proteinuria, with a mean UPCR drop of 41% and a maximum ...

A super-resolution microscopy technique offers an unparalleled glimpse into how monoclonal antibodies bind to their targets ...

Concerns about tariffs, inflation, and employment are all leading to a lot of uncertainty in the market. It also has some ...

the initiating molecule of classical complement’s potent inflammatory pathway that when misdirected can lead to tissue damage and loss. By targeting C1q, our immunotherapies are designed to stop this ...

Bad breath (medically known as halitosis) is a symptom of gastrointestinal (GI) conditions, such as acid reflux and ulcers.

and by activating the complement cascade. Augello et al. assess long-term immune responses to Omicron BA.4/5 booster in people living with HIV. The vaccine enhances immunity, with T cell responses ...