Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and ...
To determine whether C1q has a role in synapse elimination, the authors examined mice deficient in C1q (C1qa-knockout mice), in which the complement cascade cannot be activated. Defects in synapse ...
By silencing C3, investigational ARO-C3 has the potential to treat complement-mediated renal diseases by modulating the activation of the complement cascade. Also Read: Veren Soars On Whitecap ...
Similar to the coagulation system, the complement system consists of a cascade of proteases that is triggered by particular extracellular signals and leads to membrane attack complexes and ...
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A preclinical biotechnology company, spun out of The University of Manchester, has announced the completion of a €72 million finance deal to develop the treatment of a leading cause of blindness. The ...
An ongoing open-label, single arm, POC study is evaluating ANX1502 in patients with cold agglutinin disease (CAD) for up to four weeks to evaluate tolerability, pharmacokinetics, pharmacodynamic and ...