For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.

The paper M.S. Levine et al., “Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals,” Dev Cell, 40:313-22, 2017. Three’s a crowd More than a century ago, the German ...

We have taken the new approach of using centrosome amplification, a tumor-associated phenomenon, to rank tumors so that genes associated with this phenomenon can be identified for further study.