This includes understanding the role of target genes in healthy and diseased cells, unraveling molecular pathways, designing gene therapeutic approaches, cellular reprogramming and many more. Thus, ...

Academic research trends continue to drive transfection technology advancements. Researchers hope to use more biologically relevant yet hard-to-transfect cell models in addition to the standard ...

Researchers deliver transfected nucleic acids as oligonucleotides or in a viral or plasmid vector, which carries the genetic material into the host cells. Transfection can be stable or transient.

DNA transfection is generally preferred for long-term, stable expression and for integration into the host genome—useful when generating stable cell lines. It’s also beneficial for CRISPR ...

Recent advances have allowed transient protein expression to become a fast, flexible, and economical way to produce high-quality recombinant proteins without the time and cost associated with ...

Research was carried out utilizing the protocol demonstrated in the T-cell transfection workflow shown in Figure 1. Transfection was carried out on day 0 (Figure 1). T-cells were washed and then ...

Intravenous endostatin gene transfection results in ... clone was transfected with empty vector. Cell migration and invasion assays were carried out using the BD FALCON HTS Fluoroblok insert ...

making the selection of the right transfection reagent crucial for achieving high-efficiency cell lines with low cytotoxicity for both clinical and research applications. Polyethylenimine (PEI) has a ...

The CellPore™ Transfection System represents a substantial leap forward for cell engineering researchers, offering a novel method—known as mechanoporation—for cargo delivery into mammalian ...

Principal Scientist in Sartorius’s Cell Biology Development Group, looks at some of the many advantages and best practice approaches to transfection. Read the full story here.

VANCOUVER, British Columbia — STEMCELL Technologies has commercially launched the CellPore™ Transfection System, providing a groundbreaking new technology with the potential to advance cell ...