The primary pharmacokinetic interactions with smoking occur with drugs that are CYP1A2 substrates, such as caffeine, clozapine, fluvoxamine, olanzapine, tacrine, and theophylline. Inhaled insulin ...
Cytochrome P450 (CYP) enzymes play a central role in the degradation of drugs. Particularly relevant for human drug metabolism are CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4. Due to genetic variations ...
Purpose: Gastric cancer (GC) ranks as the third most common cause of cancer related mortality and as the fifth most frequently diagnosed cancer globally. Less than 30% of people with GC survive for ...
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