Aspirin and COX-1 inhibitors boost immunity against cancer metastasis, revealing a new pathway for anti-metastatic therapies.

This simplistic division of the roles of COX-1 and COX-2 drove the search for 'selective' COX-2 inhibitors and further ... Multiple experimental variables (e.g., substrate concentration, time ...

The Lancet Respiratory Medicine published a phase 2 clinical study article on China's first DPP-1 inhibitor, HSK31858, led by ...

From the crude animal tissue preparations initially used in vitro (e.g., homogenate of guinea ... the differing physiological roles of COX-1 and COX-2, development of 'new' NSAIDs was aimed ...

TNF inhibitor use demonstrates no negative impact on survival among patients recently diagnosed with colorectal, lung or ...

Travere Therapeutics, Inc., today announced that the Company will present three abstracts, including one late-breaking oral presentation, at the upcoming National Kidney Foundation (NKF) Spring ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.