X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in ...

X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in T-cell, B-cell, and natural ...

“Gene therapy for hemophilia A with the use of lentiviral vector-transduced autologous HSCs resulted in stable factor VIII ...

CellProthera, a regenerative cell therapy developer specializing in ischemic diseases, announced it will be presenting next week at Terrapinn’s Advanced Therapies Congress 2025, held in London. Ibon ...

Tremtelectogene empogeditemcel (trem-cel) may make gemtuzumab ozogamicin maintenance safer for patients with high-risk acute myeloid leukemia (AML), according to results of a phase 1/2 trial presented ...

Results from the single-arm open-label trial have been able to elicit an extension of CD34+ cells ex vivo in two out of the 12 patients enrolled on the trial. The trial data, published in the New ...

Discover how hyperbaric oxygen therapy influences telomeres, stem cells, and mitochondria. New research reveals promising ...

Data published in NEJM Evidence detail the first clinical test of ZSCAN4 for telomere elongation. Treatment with EXG-34217 resulted in in vivo telomere elongation in a subpopulation of lymphocytes to ...

The Rome-based charity recently applied for marketing authorization of the same gene therapy, previously advanced by Orchard Therapeutics, in the EU.

Based on early Phase I/II data, investigators at Cincinnati Children's are enrolling more patients with a telomere biology ...

After two decades of tracking the elusive blood stem cells, Civin developed the CD34 antibody, which worked as a literal stem cell magnet, picking out these rare cells. The breakthrough made it ...

On immunohistochemistry (IHC), tumor cells were positive for Tdt (strong diffuse nuclear expression) and focally expressed CD34 and CD20 (Figure 3). Strong and diffuse expression was also noted for ...