Frontiers13d
Gravacin as an inhibitor of the auxin transport-activating protein kinase D6PK in Arabidopsis
A Biacore 8K system (Cytiva) was used to measure the binding affinity at 25°C with a flow rate of 30 µl min −1. Purified D6PK proteins were immobilized onto the series S CM5 sensor chips (Cytiva) by ...
C&EN11d
Three-Dimensional Polyglycerol–PEG-Based Hydrogels as a Universal High-Sensitivity Platform for SPR Analysis
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. We developed a three-dimensional (3D) polyglycerol–poly(ethylene glycol)-based ...
eLife12d
Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings
By leveraging the concept of coevolved dynamical couplings—residue pairs with critical dynamical interactions that have been preserved during evolution—DyNoPy offers a powerful method for predicting ...
C&EN12d
Optimization of Cyclophilin B-Targeted Tri-vector Inhibitors for Novel MASH Treatments
EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, Scotland EH9 3FJ, U.K.