The drug – a combination of beta-lactam antibiotic aztreonam with beta-lactamase inhibitor avibactam – is the first monobactam/β-lactamase inhibitor combination to be cleared in the US for ...

AMR Action Fund said this morning that the first ... a pipeline of novel combinations of beta-lactam antimicrobials and beta-lactamase inhibitors – drugs used alongside the antibiotics to ...

It has also been suggested that one drug be used to inhibit bacterial penicillinase action sufficiently for ... by competititive inhibition of a β-lactamase have been demonstrated for pseudomonas ...

Cefuroxime has activity in the presence of some beta-lactamases, both penicillinases and cephalosporinases, of Gram-negative and Gram-positive bacteria. Use IV route for serious infections.

Among children treated with an oral agent, the recurrence rate was 16/42 (38.1%) following penicillin or amoxicillin and 10/36 (27.8%) following a beta-lactamase resistant agent (adjusted odds ...

that may inactivate certain beta-lactamase enzymes. <3months: not recommended. Take with food. Base dose on amoxicillin component. Due to clavulanic acid component, ES-600 is not interchangable ...

This rate is higher than observed in children treated with a beta-lactamase resistant agent, although the associated risk estimate reached statistical significance (pooled OR: 2.39 [95% CI ...