Antacids work quickly to neutralize stomach acid, while H2 blockers and PPIs reduce the amount of acid your stomach produces. The best OTC medication for heartburn and acid reflux will depend on ...

Headache risk was also 40 percent higher among those using H2 blockers drugs and 30 percent higher among those taking common antacids such as Tums or Alka-Seltzer. Described in the study as the ...