Aspirin was introduced into clinical medicine ... At the same time, there was sufficient evidence to suggest a link between COX inhibition and adverse gastrointestinal and renal effects.

The study demonstrates that cyclooxygenase 1 (COX-1) inhibitors, including aspirin, enhance immunity to cancer metastasis by ...

1). This statistic might seem surprising — after all, the therapeutic use of COX inhibitors has a venerable history dating back to the introduction of aspirin in 1898 (or even earlier if the use ...

The effects of aspirin, nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), and cyclooxygenase (COX)-2 specific inhibitors on prostaglandins (PGD2, PGF2a, PGE2, PGH2) synthesis PGI ...