Around 1 in 6 older adults take aspirin as their primary method of preventing cardiovascular disease – despite stricter ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Patients with antiphospholipid antibodies (aPL) are at increased risk for arterial or venous thrombosis. There is, however, significant heterogeneity among patients according to clinical and ...

Provocation with aspirin in AIA patients produces airflow obstruction accompanied by the release of cysteinyl LTs into the urine and BAL fluid. [7, 8] LTC 4 synthase is the rate-limiting enzyme ...

Mohit K Turagam; Poonam Velagapudi; Miguel A Leal; Abraham G Kocheril Disclosures Expert Rev Cardiovasc Ther. 2012;10 (4):433-439.

Inclusion criteria: Adults (18 years old or older) taking antiplatelet drugs for at least 2 weeks; scheduled for elective or emergency neurosurgery under general anaesthesia (craniotomy, spinal cord ...

Aspirin prodrugs formed by derivatization at the benzoic acid group are very difficult to obtain because the promoiety accelerates the rate of hydrolysis by plasma esterases at the neighboring acetyl ...

MINNEAPOLIS — Universal presumption of low-dose aspirin, instead of risk-based screenings, can increase uptake for preeclampsia prevention in underserved populations, according to a speaker at ...

Compared with aspirin, clopidogrel reduces risk of mortality, myocardial infarction (MI), and stroke after percutaneous coronary intervention (PCI) and completion of a standard duration of dual ...

Resistance and nonresponse to aspirin dramatically decreases its therapeutic efficacy. To overcome this issue, a small-molecule thrombus-targeting drug delivery system, aspirin-Arg-Gly-Asp-Val (A-RGDV ...

High-dose aspirin (HDA) is used with intravenous immunoglobulin (IVIg) in Kawasaki disease (KD). Practice regarding HDA varies, and it is unclear whether HDA duration affects the long-term course ...

AI reveals hidden language patterns and likely authorship in the Bible by Duke University edited by Sadie Harley, reviewed by Robert Egan Editors' notes ...