Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

The humanization of the Ig loci was carried out in a 129S6 ... The allelic forms of IgM can be distinguished by flow cytometry using specific antibodies. Although the mature B-cell populations in ...

NASHVILLE, Tenn. (WSMV) - Vanderbilt University Medical Center will lead a massive project aimed at discovering therapeutic antibodies through the use of Artificial Intelligence. Therapeutic ...

An effective HIV-1 vaccine must therefore elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies (bnAbs) have been isolated from HIV-1 infected ...

Share on Pinterest Scientists have found that an antibody treatment prevented a decline in muscle mass and bone density after using GLP-1 drugs. Rob and Julia Campbell/Stocksy Aging and limited ...

The potential of monoclonal antibodies (mAbs) as therapies is indisputable. The current mAbs market is expected to be around ~USD 150 billion. In 2021, five out of the top 10 selling drugs were ...

They also examined the associations between putative enhancers and GWAS-identified loci implicated in neuronal disorders. The researchers identified 47,350 putative enhancers, 65.6% of which were ...

More information: Julian Daniel Sunday Willett et al, Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses, Alzheimer's & Dementia (2025). DOI: 10.1002/alz.14592 .

Researchers at the University of Texas Health Science Center at San Antonio (UT Health San Antonio) have published a study analyzing more than 30 years of aging and dementia patterns of 678 nuns ...