[97–99] There are two main causes for the bacteria-induced thrombocytopenia: Bacteria induce platelet activation. Activated platelets show shortened survival and are targets of phagocytic ...

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread out to stop the blood from leaking out. Once enough layers of platelets ...

CNIO researchers found that in mice on high-fat diets, cancer cells in the bloodstream use platelets as a protective shield, ...

Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread ...

The currently available antiplatelet drugs target key steps of platelet activation including thromboxane A 2 synthesis, ADP-mediated signaling, and glycoprotein IIb/IIIa-mediated platelet aggregation.

Class, Polyphosphate (polyP)-Based Therapy, Show Promise in Bypassing P2Y12 Inhibition to Restore Normal Clotting Function ...

A BLA has been filed for bentracimab and, if approved, has the potential to be the first therapy to reverse the effects of ...

different signaling molecules were activated depending on the endpoint. Using human platelet-rich plasma, the researchers found that when certain signaling molecules were inhibited, spreading was ...

CNIO researchers discover that, in mice that eat a lot of fat, cancer cells travelling through the blood surround themselves with platelets, which act as an armor-like protection as they spread. In ...