Frontiers20d
HSF1 at the crossroads of chemoresistance: from current insights to future horizons in cell death mechanisms
HSF1 participates in DNA damage repair by forming interactions with PARP1 and PARP13, facilitating the localization of PARP1 to DNA single-strain break sites and regulating RAD51 or 53BP1 during ...
eLife26d
Replication stress inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors
(B and C) γH2AX and 53BP1 foci of MCF10A cells transfected with siNC or siELF3 for 48 h and treated with 2 mM HU for 4 h followed by release for 20 h (mean ± SEM, n > 100, unpaired two-tailed ...
The EMBO Journal16d
The microcephaly-associated transcriptional regulator AUTS2 cooperates with Polycomb complex PRC2 to produce upper-layer neurons in mice
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AUTS2 syndrome patients often exhibit ...
GitHub18d
Reactive Oxygen Species Machine Learning Project
This is the machine learning pipeline and web service of the research: Single-cell Reactive Oxygen Species Regulome Profiling Reveals Dynamic Redox Regulation in Immune Cells Yi-Chuan Wang; Ping-Hsun ...