How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing medicines targeting metalloenzymes, announced today that it will present preclinical data on its ...

T cells play a pivotal role in the immune system by transforming into powerful effector cells that combat pathogens. This transformation requires rapid proliferation, during which DNA replication ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

Using DNA nanorobots, the researchers were able to influence the shape and functionality of these synthetic cells. New transport channels for proteins and enzymes DNA nanotechnology is one of Laura Na ...

Advances in DNA nanotechnology now offer promising solutions ... this system can facilitate the transportation of therapeutic proteins or enzymes to their targets in the cell.

They applied the new method to more than 1,500 European genomes (a person's complete set of DNA) from people who lived primarily during the first millennium AD (year 1 to 1000), encompassing the ...

Mansfield Police Chief Jason Bammann said the cold case of Debra Lee Miller, a local waitress beaten to death with an oven grate in her apartment on April 29, 1981, was reopened in 2021 to account for ...

As she worked at her computer, the results revealed the sample she was examining contained human DNA. There was nothing so unusual about that in itself: at the time, the ancient DNA (aDNA ...

We show here that the chief enzyme that maintains mammalian DNA ... replication. You have full access to this article via your institution. Figure 3: Map and amino acid sequence of DMAP1. Figure 4 ...