Journal of Neurology, Neurosurgery and Psychiatry (JNNP)

MRI characteristics during attack and remission distinguish patients with MOG antibody-associated disease from multiple sclerosis

Background Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and multiple sclerosis (MS) have both ...
BMJ

Are men at greater risk for Parkinson’s disease than women?

1 Department of Neurology, University of Virginia School of Medicine, Charlottesville, USA 2 Department of Health Evaluation Sciences, University of Virginia School of Medicine Correspondence to: Dr G ...
BMJ

Clinical management of spasticity

Correspondence to: Professor Alan J Thompson Institute of Neurology, Queen Square, London WC1N 3BG, UK; a.thompsonion.ucl.ac.uk Spasticity is a common symptom seen in many neurological conditions, ...
BMJ

Prognostic relevance of quantitative and longitudinal MOG antibody testing in patients with MOGAD: a multicentre retrospective study

Background IgG antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) define a subset of associated disorders (myelin oligodendrocyte glycoprotein associated disorders (MOGAD)) that can have ...
BMJ

Left atrial appendage occlusion in patients with atrial fibrillation and intracerebral haemorrhage associated with cerebral amyloid angiopathy: a multicentre observational ...

Background Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral haemorrhage (ICH) with a high recurrence risk. Left atrial appendage occlusion (LAAO) is a method for ischaemic stroke ...
BMJ

The EQ-5D—a generic quality of life measure—is a useful instrument to measure quality of life in patients with Parkinson's disease

OBJECTIVE To test the feasibility and validity of the EQ-5D (a widely used generic (disease non-specific) quality of life (QoL) instrument which allows comparisons between different patient groups and ...
BMJ

Accelerating assessment of disease modification in Parkinsons via multi-arm, multi-stage design: the EJS ACT-PD initiative

Background Identifying a disease-modifying therapy (DMT) for Parkinson’s disease (PD) is a major unmet need. Inefficiencies in the current clinical trials process have resulted in lengthy evaluation ...
BMJ

Comparison of indices of traumatic brain injury severity: Glasgow Coma Scale, length of coma and post-traumatic amnesia

Background: Classification of traumatic brain injury (TBI) severity guides management and contributes to determination of prognosis. Common indicators of TBI severity include Glasgow Coma Scale (GCS) ...
BMJ

Homocysteine, folate, methylation, and monoamine metabolism in depression

Dr E H Reynolds, Institute of Epileptology, Weston Education Centre, King's College, Denmark Hill Campus, London SE5 9PJ, UK reynolds{at}buckles.u-net.com Present address for T Bottiglieri Institute ...
BMJ

Lacrimation, conjunctival injection, nasal symptoms… cluster headache, migraine and cranial autonomic symptoms in primary headache disorders—what’s new?

Correspondence to Professor P J Goadsby, UCSF Headache Center, 1635 Divisadero St, Suite 520, San Francisco CA 94115 USA; pgoadsby{at}headache.ucsf.edu If you wish to reuse any or all of this article ...
BMJ

Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: a cohort study

Objective: There are only limited epidemiological studies evaluating the association between vertebrobasilar dolichoectasia (VBD) and outcomes. This study was designed to elucidate the outcome and ...
BMJ

Changes in appetite, food preference, and eating habits in frontotemporal dementia and Alzheimer’s disease

4 MRC Cognition and Brain Sciences Unit and University of Cambridge Neurology Unit, Addenbrooke’s Hospital, Cambridge, UK Correspondence to: Professor J R Hodges, MRC Cognition and Brain Sciences Unit ...