a phenomenon called RNA interference or RNAi. The apparently widespread nature of RNAi in eukaryotes, ranging from trypanosome to mouse, has sparked great interest from both applied and ...

RNA interference (RNAi) acts like a "gene switch," selectively silencing specific genes. It uses specialized RNA molecules, such as small interfering RNA (siRNA) or microRNA (miRNA), to block ...

In 1998, Andrew Fire and Craig Mello published a groundbreaking study demonstrating that double-stranded RNA (dsRNA) could silence genes in the nematode Caenorhabditis elegans. This discovery laid the ...

View Full Profile. Learn about our Editorial Policies. The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi ...

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of ...

It has only been 5 years since Tom Tuschl and colleagues showed that the RNA interference (RNAi) pathway was functional in cultured mammalian cells, and that it was possible to trigger this ...

RNA interference (RNAi) is a cellular mechanism that uses small RNA molecules, such as small interfering RNAs (siRNAs) and miRNAs, to silence gene expression. These small RNAs can bind to ...

Renaissance BioScience Co-CEO John Husnik shares insight on the company’s yeast-based RNA-interference biopesticide ...

Despite growing competition in the transthyretin amyloid cardiomyopathy (ATTR-CM) field, Alnylam is hoping its RNA interference approach can set it apart from its peers. And now, the Massachusetts ...