In patients with stage II-III rectal cancer, non-operative management after a clinical complete response to neoadjuvant ...

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Organ preservation may be a viable option for select patients with locally advanced rectal cancer, according to the first results of the NO-CUT trial. The study investigated the efficacy of total ...

SOC was dominated by TNT with selective NOM in the base case analysis. TNT in which CRT was followed by consolidation chemotherapy (CNCT) was the least costly at $89,712 in Medicare proportionate US ...

A new treatment for locally advanced rectal cancer (LARC) has proved successful enough to avoid surgery and reduce the risk of recurrence, according to a new study. Total neaoadjuvant treatment (TNT) ...

In recent years total neoadjuvant treatment (TNT)—a potent new treatment approach for advanced colorectal cancer that confronts tumors with aggressive rounds of chemotherapy and chemoradiation ...

ARLINGTON, Va., November 25, 2024 — The American Society for Radiation Oncology (ASTRO) issued today an updated clinical guideline for physicians who use radiation therapy to treat patients with ...

Distance relapse-free survival was maintained in patients with pMMR locally advanced rectal cancer through non-operative management of the disease. Patients with mismatch repair proficient (pMMR) ...

Although rectal cancer is a life-threatening disease, it is highly curable in its early stages. Depending on the location and state of the cancer, surgery may be required. To avoid life-altering ...

Chemotherapy and radiotherapy may be efficacious enough for certain patients with advanced rectal cancer to avoid surgery, research showed. Upfront chemotherapy and radiotherapy may help reduce the ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...