A new microscopy method enables researchers to visualize the activity of the enzymes caspase-3 and alkaline phosphatase in various biological samples (Nat. Methods 2024, DOI: ...

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

Rapid 3D image acquisition technique, without moving observation plane, developed by Tohoku and Osaka universities. Conceptual illustration of the “One-scan” microscopy method. A newly-proposed 3D ...

Super-resolution microscopy methods are essential for uncovering the structures of cells and the dynamics of molecules. Since researchers overcame the resolution limit of around 250 nanometers (while ...

Researchers have adapted a class of techniques employed in astronomy to unblur images of far-away galaxies for use in the life sciences, providing biologists with a faster and cheaper way to get ...

Chemotherapy is a powerful weapon against cancer, but certain cells resist treatment by entering a dormant stage called senescence. These therapy-induced senescent (TIS) cells may become resistant to ...

In terms of resolution, SIMIP achieved a 1.5-fold improvement over conventional MIR photothermal imaging, with a full width at half-maximum (FWHM) of 335 nm versus 444 nm in standard methods. Moreover ...

How flu viruses enter cells has been directly observed thanks to a new microscopy technique with the potential to revolutionize research on membrane biology, virus–host interactions and drug discovery ...

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging ...

A new microscopy method enables researchers to visualize the activity of the enzymes caspase-3 and alkaline phosphatase in various biological samples (Nat. Methods 2024, DOI: ...