Transcription is the first step in decoding a cell's genetic information. ... In fact, rRNA is sometimes called a ribozyme or catalytic RNA to reflect this function.

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

The conversion of ribosomal DNA to ribosomal RNA (rRNA), i.e., transcription, is thought to be a rate-limiting step of biogenesis (the slowest step that determines the speed of the ribosome ...

Ribosomal RNA (rRNA) is a type of non-coding RNA that is a crucial component of ribosomes, the cellular machinery responsible for protein synthesis.Non-coding RNA refers to RNA molecules that are not ...

rRNA transcription. The single pre-rRNA transcription unit (pre-rRNA gene) induces the formation of a nucleolus and the other components of a ribosome diffuse to the newly formed pre-rRNA.

Ribosomal RNA synthesis accounts for up to 70 percent of total RNA synthesis in E. coli cells." ... Structural basis of ribosomal RNA transcription regulation. Nature Communications, 2021; 12 (1) ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

DHX36 specifically binds to G4 structures on DNA (particularly in rDNA regions and transcription start sites) and pre-rRNA, thereby regulating chromatin conformation, ...

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