A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Expansion of the eukaryotic proteome by alternative splicing ... Cell signalling and the control of pre-mRNA splicing. Nature Reviews Molecular Cell Biology 5, 727–738 (2004) doi:10.1038 ...

What's the difference between mRNA and pre-mRNA ... sequences at their splice sites, eukaryotic genes with long introns also contain exonic splicing enhancers (ESEs). These sequences, which ...

1 Alternative splicing will sometimes introduce a premature stop codon into an mRNA, which NMD will recognize as an mRNA ... in defining cell phenotypes and physiology in multicellular eukaryotes, ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

The polyadenylation process is akin to adding a marquee sign, ensuring that the mRNA stays recognizable and functional long enough to be translated into proteins. Splicing Enzymes: The Editors ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

eventually zeroing in on pre-mRNA splicing for many years. This splicing removes introns from RNA before translation and dictates how a gene will be expressed. This flexible form of expression helps ...