Undertaking single-cell RNA sequencing, they found that ZBTB12 inhibits dedifferentiation. hPSCs with a deficiency of ZBTB12 dedifferentiated into more primitive stem cells.

Stem cells are ... For example, red blood cells are specifically designed to carry oxygen through the blood. All humans start out as only one cell. This cell is called a zygote, or a fertilized ...

Somatic cells within an organism share the same genomic sequence, but when development occurs from the single-cell zygote ... biasing the differentiation potential of iPSCs toward lineages ...

We provide scalable new tools, which include mosaic models and downstream multiplexing, for longitudinal single-cell profiling of brain organoids derived from multiple individuals. In addition ...

However, because HoxB4 appears to promote the differentiation of embryonic stem cells into ... from a fertilized zygote have the potential to produce an embryonic stem-cell line, and these cells ...

In their study, published in Mechanobiology in Medicine, the researchers discovered that the protein responsible for binding neural stem cells in ... neural stem cell differentiation in ...

For example, the zygote formed during the ... during the early stages of embryonic stem cell differentiation. Multipotent, oligopotent, and unipotent cells Multipotent cells can divide into ...

This single-celled zygote then starts to divide, forming 2, 4, 8, 16 cells ... cell division and differentiation are responsible for conditions that include cancer and congenital disabilities that ...

Stem cell signaling: Molecular morse code in stem cells encrypting differentiation information. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 02 ...

Mesenchymal stem cells (MSCs), which can be harvested from fat and bone marrow, have immune-modulating and anti-inflammatory ...