So, why is there a need to make a switch in the ... The doctor you are see may suggest you to switch from SSRI to SNRI. While SNRIs enhance both serotonin and norepinephrine levels, as the name ...

While the effectiveness of esketamine combined with either SSRI or SNRI in treating TRD has been widely explored, it has been unclear which pairing has the advantage in different clinical aspects.

Treatment with esketamine combined with an SNRI is linked to fewer adverse outcomes than treatment with an SSRI alone.

The studies' author's call on doctors to rethink their use. Psychiatrists and GPs increasingly combine mirtazapine with an SSRI (selective serotonin reuptake inhibitor) or SNRI (serotonin-noradenaline ...

in addition to current antidepressant SSRI/SNRI therapy, for 42 days. The primary endpoint for both trials was the change from baseline to day 43 in Montgomery-Åsberg Depression Rating Scale ...