The lac repressor, which is produced from the lacl gene, regulates the transcription of the lac operon. The repressor binds to the lac operator to inhibit its transcription.

For example, repression of the lac operon by its repressor, called lacI, is inhibited by the ligand allolactose, to which the repressor protein directly binds. Thus, lactose, from which ...

The 92-year-old bacterial geneticist who helped pioneer the study of gene regulation has passed away. A series of rodent experiments showed that even with abundant food and water, personal space is ...

Monod and Jacob's lac operon turned out to be the first of many bacterial operons. But by the late 1960s, it was clear that operons weren't the biological norm. None have ever been found in humans ...

Last week I finally addressed promoters and gave a bit of background on the lac operon. Looking back, I feel that I didn't give the topic of operons adequate treatment. They are a very crucial ...