Scientists in the lab of chemical engineer Monther Abu-Remaileh are uncovering the cellular functions that go awry in ...

To break down and recycle these nutrients, the cells rely on tiny organelles called lysosomes. When functional, a lysosome ...

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

Dr. Dominic Winter is researching how this “recycling center” works – and how defects in its composition play a role in cancer. The German Research Foundation has awarded Winter a Heisenberg ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes ...

The lysosome is a small membrane bound organelle that can be found in most animal cells. It was once thought that these little sacs were like recycling centers that could take up cellular waste ...

An international team led by EPFL has discovered a powerful anti-aging pathway in roundworms, revealing how boosting the cell ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed.

Enzymes and lysosomes People with lysosomal storage disorders lack important enzymes (proteins that speed up reactions in the body). Without those enzymes, the lysosome isn't able to break down ...

Researchers identify the PITT pathway, the mechanism through which lysosome membranes are repaired in healthy cells.