Enzymes are often held in this appropriate conformation by small molecules called cofactors. I am fond of cofactors. I appreciate how, despite their structural simplicity, these helper molecules play ...

The biosynthetic pathways leading to both types of cofactor have common mechanistic ... were localized within the mitochondrial matrix (R.R.M., unpublished observations), which necessitates ...

These are known as cofactors, and without these enzymes remain within the inactive “apoenzyme” forms. Once the cofactor is added, the enzyme becomes the active “holoenzyme”. Cofactors can ...