Together, these findings have uncovered a potential role for the Notch pathway in cardiac development and provide an approach for generating large numbers of cardiac progenitors from ES cells.

Human mutations in Notch signalling components have been implicated in several forms of congenital cardiovascular disease, including cardiac outflow tract defects (jagged 1, notch 2), aortic valve ...

Ligands and receptors that make up the NOTCH signaling pathway help to create the valves that funnel blood into the aorta in a unidirectional manner with each beat of the heart. NOTCH promotes this ...

Information hasn't been released about what caused him to suffer the condition, or what's next for him in the coming days. Gounder said that elite athletes typically undergo some kind of cardiac ...