Because protein synthesis and secretion rates vary dramatically ... Both PERK and IRE1α are type I transmembrane proteins with similar ER luminal domain structures and a cytosolic Ser/Thr kinase ...

On the other hand, cell-free protein synthesis technologies have other drawbacks such ... We used this method to successfully produce many types of human-derived multipass transmembrane proteins and ...

Calcium is stockpiled in intracellular depots located within the endoplasmic reticulum (ER), a network of tubules and membrane sheets that plays a central role in the synthesis of lipids and proteins.

Only two target complex transmembrane proteins like G-protein-coupled receptors (GPCRs) 2. What are the established and emerging membrane protein targets for antibody therapies? Established ...