We noted that two of these glycolytic intermediates, fructose-6-phosphate and glyceraldehyde-3-phosphate, are also the final products of the transketolase reaction, which is the rate-limiting ...

The nonoxidative part of the PPP is controlled by transketolase enzyme reactions. We have detected upregulation of a mutated transketolase transcript (TKTL1) in human malignancies, whereas ...