Most drug-induced renal injuries affect the proximal tubules. Drug toxicity initially targeted to the glomerulus or more distal parts of the nephron may also cause secondary injury to proximal ...

Three different hTERT-immortalized human primary renal proximal tubule epithelial cells (RPTEC) were modified and tested for functionality and stable expression of the OAT1, OCT2, and OAT3 proteins.

Transform your drug development pipeline with Newcells’ Renal Proximal Tubule Cells Model eBook ... to measure cilia beat frequency and toxicity on small airway epithelial cells model, retinal ...

Renal tubule epithelial cells can be oval to columnar ... possibility of a metabolic disorder or acute renal failure due to toxicity. [9] The authors have no relevant affiliations or financial ...

Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

Toxic puberulic acid found in Kobayashi Pharmaceutical Co.’s dietary supplements that led to widespread health damage can cause renal tubular necrosis, the health ministry said, citing animal ...