Toxic megacolon is a rare but reported presentation of severe pseudomembranous colitis. This article reviews the reported cases of Clostridium difficile with toxic megacolon in the literature and ...

Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon complicating ulcerative colitis. Myasthenia gravis. Ileostomy or colostomy. Autonomic neuropathy.

CDI presents in a wide range of severity, from mild diarrhea to life-threatening complications like toxic megacolon. Risk factors include antibiotic use, advanced age, immunosuppression ...

and anasarca without toxic megacolon. The patient responded slowly to medical therapy consisting of intravenous metronidazole, oral vancomycin, and parenteral nutrition. Subsequently ...