Negative selection in fetal thymus clonally deletes many self-reactive T cells, permanently removing ... factor regulating genes implicated in Treg development was confirmed.

Researchers from the Wellcome Sanger Institute and their collaborators at Ghent University, Belgium, the National Institutes of Health's National Institute of Allergy and Infectious Diseases and ...

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical ...

There is potential for Tregs and amphiregulin to be used in patients receiving cancer therapies to ameliorate immune function.

The fetal thymus is a crucial organ for the development of the immune system, playing a significant role in the maturation of T-cells, which are essential for immune responses. Recent research has ...

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organization ...

including T cell lymphocytes which are matured in the thymus. The fundamental discovery of the key role that the thymus plays in the development of our immune system underpins our understanding of ...

The thymus produces T cells, which help the body to fight infection ... research say their findings could be significant in ...

T-cell glucocorticoid receptor deletion. (a) Exon 2 was flanked by loxP sites () for targeted deletion of Nr3c1. WT, wild-type. (b) Southern blot analysis of heart (H), thymus (T), kidney (K ...

He uses mouse models to study the thymus, the organ in which specialized immune cells called T cells mature. His goal is to apply his findings to develop new therapies to promote immunity in cancer ...

Vaccines that generate high levels of antibodies do not necessarily generate high levels of T cells. "Development of vaccines must incorporate the viral components that T cells recognize and react ...