Toll-like receptors (TLR) make the first contact with invading bacteria and function as sensors of infection for immune cells. But the signalling pathway is apparently ... that helps explain the ...

B) This model, based on x-ray crystallography data, shows how the amino acid chain of a TLR folds up to form a ... creates a signal transduction pathway that links an activated receptor to its ...

Research published in Nature indicates that persistent signaling downstream of Toll-like receptor (TLR)-7 and ... for TLR7 and TLR9 in promoting the IFN pathway in SLE, and the inability of ...

These peptides inhibited TLR signaling in macrophages ... sought to overcome these limitations by targeting TLR pathways ...