First, three initiation factor proteins (known as IF1, IF2, and IF3) bind to the small subunit of the ribosome. This preinitiation complex and a methionine-carrying tRNA then bind to the mRNA ...

The ribosome has a small and a large subunit and is a complex molecule composed of several ribosomal RNA molecules and a number of proteins. Translation of an mRNA molecule by the ribosome occurs ...

Macrolides bind reversibly to 23S ribosomal RNA (rRNA) of the 50S subunit of bacterial ... that binds to the 50S ribosome to prevent the formation of the 70S initiation complex, is also capable ...