What Is Mevalonate Kinase Deficiency? Mevalonate kinase deficiency (MKD) is a disease that runs in families. A problem with your immune system causes attacks of fever and symptoms like swollen ...

Elevated core body temperatures may cause bursts of inflammation in individuals with rare autoinflammatory mevalonate kinase deficiency (MKD) via a unique molecular mechanism, reports a study ...

A deficiency of mevalonate kinase resulting in mevalonic aciduria was the first inherited defect in cholesterol and nonsterol isoprene biosynthesis to be recognized. 1 Nine other enzyme ...

Familial Mediterranean fever, mevalonate kinase deficiency (also known as the hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor receptor–associated periodic syndrome (TRAPS ...

It’s also called hyper-IgD syndrome, or HIDS. It’s a less severe form of a metabolic disorder called mevalonate kinase deficiency (MKD). HIDS is something you’re born with. Symptoms ...

Scientists have found strong genetic evidence of a link between mutations of the mevalonate kinase gene (MVK) and disseminated superficial actinic porokeratosis (DSAP). It is a major step toward ...