Figure 2: Structure of the CmoA–Cx-SAM complex ... In summary, direct structural observation identified the novel metabolite Cx-SAM, leading to the discovery of unique Cx-SAM synthase and ...

Structure of the molecular machine that links carbohydrate and lipid metabolism. ScienceDaily . Retrieved May 21, 2025 from www.sciencedaily.com / releases / 2019 / 04 / 190403135009.htm ...

Precise definition of small molecules is hindered by the fact that they rapidly lose any resemblance to the parent structure. Metabolite can also represent a building block of a larger structure ...

MS2Mol is designed to predict the structure of metabolites, which are the building blocks and breakdown products of the cell. Despite their essential role in all cell processes, it is estimated ...

Obesity causes temporary disruptions, but not permanent structural changes, in the liver’s molecular network that regulates ...

More information: June H. Tan et al, Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing, Nature Biotechnology (2025). DOI: 10.1038/s41587-025-02554-7 ...

This year’s Lasker Basic Medical Research Award recognizes the contributions of Demis Hassabis and John Jumper for their invention of the AlphaFold artificial intelligence (AI) system, which ...

Investigators led by Issam Ben-Sahra, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered how cellular metabolism fluctuates in response to changes in levels of ...