The spike protein region of SARS-CoV-2 is the most studied structural part of the virus since most mutations that give rise to variants with increased transmissibility, and immune evasion occur in ...

In their previous work, the authors found that SARS-CoV-2 non-structural protein 2 (NSP2) impairs the host antiviral immune system using miRNA-mediated translation repression. It interacts with ...

All coronaviruses produce four primary structural proteins and multiple nonstructural proteins. However, the majority of antibody-based SARS-CoV-2 research has focused on the spike and ...

A number of structural and nonstructural proteins of SARS-COV-2 are conserved among the coronavirus species. The list of proteins provides a good starting point for researchers to search for ...

The latest in a series of structural studies of the SARS-CoV-2 variants' "spike" protein, led by Bing Chen, Ph.D., at Boston Children's Hospital, reveals new properties of the Alpha (formerly U.K ...

protein is the smallest of the four structural proteins that make up the SARS-CoV-2 viral particle and is essential for the virus to infect cells. Data from other coronaviruses led researchers to ...

Vimentin is a structural protein that is widely expressed in the cells of mesenchymal origin such as endothelial cells and a potential novel target against SARS-CoV-2, which could block the ...

SARS-CoV-2 is an RNA virus with a large genome encoding at least 29 proteins, including structural (such as the spike protein), accessory and non-structural proteins. Previous studies had shown ...

More information: Siwen Long et al, SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs, Nature Communications (2024). DOI: 10.1038/s41467-024 ...

Researchers have discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly ...