Arakoda, an 8-aminoquinolone antimalarial, was approved in 2018 for the prophylaxis of malaria in patients aged 18 years and older.

Malaria, caused by Plasmodium falciparum parasites, is a leading cause of death in children under five in many parts of Africa. Blood-stage malaria—when the parasite infects red blood cells ...

Blood-stage malaria vaccines are intended to prevent ... from the 3D7 strain of Plasmodium falciparum, has previously been shown to have immunogenicity and acceptable safety in Malian adults ...

Panel A shows the mean number of Plasmodium falciparum parasites ... the nature of protective immune responses against malaria, both stage-specific and antigen-specific, to be further investigated.

Malaria remains a persistent public health burden, with Plasmodium falciparum causing the most dangerous form of malaria and ...

Physician-scientists at Groupe de Recherche Action en Santé (GRAS) in Burkina Faso have successfully completed initial safety ...

Ghosh et al. Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins. PLoS Pathogens , 2009; 5 (1): e1000265 DOI ...

A new malaria vaccine achieves an ... and efficacy of genetically attenuated Plasmodium falciparum parasites. The trial included two phases: stage A, an open-label dose-escalation phase where ...

However, the ones that cause a significant threat are Plasmodium falciparum ... is detected at an early stage, then the patient can be given treated at home. Malaria is treated with oral drugs ...

The new case involves the parasite Plasmodium falciparum ... containing malaria is still a matter of targeting the mosquitoes, both as adults and in the larval stage. Mosquito control teams ...