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Biologists discover a new type of control over RNA splicing
In the first step of spliceosome assembly, an snRNA molecule known as U1 snRNA binds to the 5' splice site at the beginning of the intron. Until now, it had been thought that the binding strength ...
Quality assurance in the cell: Preventing defective protein blueprints
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
AZoLifeSciences on MSN1mon
LUC7 Proteins Play Key Role in RNA Splicing Control
In the first step of spliceosome assembly, an snRNA molecule known as U1 snRNA binds to the 5' splice site at the beginning ...
Nature5d
RNA splicing articles from across Nature Portfolio
Proper splicing requires efficient spliceosome assembly. Here the authors reveal that zinc finger protein 207 interacts with the U1 small nuclear ribonucleoprotein to accelerate spliceosome ...