Beyond safety and efficacy issues, many of the ethical concerns associated with modern-day somatic gene therapy research are also present in many other clinical settings. These include matters ...

Somatic gene therapy of many inborn errors of metabolism may require placement of recombinant genes into liver cells in order to provide substrates and cofactors for holoenzyme activity.

However, due to ethical concerns and technical challenges, germline gene therapy is not currently practiced in humans. Somatic gene therapy targets non-reproductive cells in the body, such as bone ...

Somatic gene mutations are those that are acquired ... When a somatic mutation is detected for which a targeted therapy has been developed, it is referred to as an actionable mutation.

Title: LTS-101: AnIntracerebroventricular Delivered AAV Gene Therapy Using a Novel ... is being used to develop a potential gene therapy to address somatic expansion in Huntington’s disease ...

Gene therapy, a technique that is revolutionizing ... groups who were brought together under Phase I of the NIH's Somatic Cell Genome Editing Consortium. Notably, the AAV were designed and ...

I work in a holistic way and where appropriate, draw on other modalities (art therapy, meditation, breathing techniques) to facilitate the expression of feelings or to work with somatic experiences.

Human gene therapy involves the insertion of DNA (or RNA) into somatic cells to produce a therapeutic effect. Gene therapy was first envisaged as an approach to treating genetic disorders. In this ...