He found that milkmaids who developed cowpox through working close to the animals day after day seemed to be protected from smallpox, the human form of the disease. • In Britain, the disease was ...

TimesMachine is an exclusive benefit for home delivery and digital subscribers. Full text is unavailable for this digitized archive article. Subscribers may view the full text of this article in ...

Mpox is a viral infection caused by the same family of viruses as smallpox. In central and western Africa it's common in certain animals, including squirrels and rats. People can become infected ...

Since smallpox vaccines in development cannot be tested for clinical efficacy, the Animal Rule will most likely be used to evaluate the efficacy of new-generation smallpox vaccines, per 21 CFR 601.90.

Samples of smallpox virus are not needed for the production or further development of new vaccines or drugs because animal model poxviruses are used instead. If smallpox were to be genetically ...

An unusual property of the smallpox virus is that it only infects humans and not animals and insects (this property was instrumental in the eradication of smallpox). After exposure to the virus, it ...

Survivors were often left pock-marked and blind. The smallpox vaccine, originally developed with virus from a milder animal disease, cowpox, led to smallpox’s global eradication in 1980 — the ...

They also stockpiled animal manure in the hope of spreading illness. Yet the defense held fast, and the siege was abandoned after five months. While the first true vaccine for smallpox was not ...

A national medical ethics group is pressuring regulators to shutter Oregon Health & Science University’s primate research ...

Not so with smallpox. To create this vaccine, you begin with another virus that is similar to the smallpox virus, yet different enough not to bring on the smallpox disease once it enters your body.