These observations led them to propose the sliding filament theory, which states that the sliding of actin past myosin generates muscle tension. Because actin is tethered to structures located at ...

It is the 50th anniversary of the internationally-renowned "sliding filament" theory, developed by Professor Jean Hanson and her colleague Professor Hugh Huxley. The ground-breaking discovery ...

As described by the well-known 'sliding filament' model, the amount of active contractile force that is produced is determined by the degree of myofilament overlap 5,6. As such, myofilament length ...