Here we show in human diseased liver and mouse models of the ductular reaction that Notch and Wnt signaling direct specification of HPCs via their ... S.J. Notch signalling: a simple pathway ...

NOTCH signaling influences these traits through interactions with other pathways like TGF-β, WNT, and hypoxia signaling. ... Simple urine sample could revolutionize early prostate cancer diagnosis.

The idea of a hierarchical relationship between Wnt and Notch signaling is also supported by studies ... I.L. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to ...

Scientists recently discovered how the Notch gene is involved in the pathogenic process leading to colon cancer. The Notch and Wnt signaling pathways play an important role in normal gut ...