The study, “Parallel Pathways for Serotonin Biosynthesis and Metabolism in C. elegans,” challenges the existing knowledge of how serotonin is produced and what happens to the neurotransmitter ...

Scientists are only just now learning about the roles these intestinal serotonin secretions play in regulating everything from our gastrointestinal movements, to our general metabolism.

The metabolism of tryptophan within the human body can follow one of two pathways, toward serotonin or toward production of kynurenine, a substance that plays a role in niacin production.

Amino acid decarboxylase The reaction in this pathway that is mediated by tryptophan hydroxylase is the rate limiting step, meaning that if this enzyme is blocked, the synthesis of serotonin would ...

The conversion ratio for the synthesis pathways is roughly 67 mg of tryptophan to make 1 mg of niacin. The decision to route essential tryptophan stores into either serotonin, or to NAD is made ...

Alterations in Central-nervous-system function occurred that may have been related to effects of the drug on serotonin or phenylalanine metabolism. These preliminary studies suggest that effective ...

Research over the last decade has focused on understanding the shift in calcium metabolism, with an emphasis on the relationship of serotonin with calcium during the transition period and lactation.

significantly modifying intestinal gene expression related to nutrient metabolism and amino acid absorption, rather than serotonin synthesis. Thus, disrupted amino acid transport is likely a key ...

Serotonin in the gut is considered a regulator of normal gut function and is a key driver of metabolism and metabolic disorders, said researchers. Flinders University researchers have discovered ...