Purpose: The pharmacology, pharmacokinetics ... Summary: Duloxetine is a balanced selective serotonin and norepinephrine-reuptake inhibitor available in the United States for the treatment ...

Serotonin can promote both pulmonary vasoconstriction and pulmonary vascular remodeling and is thought to be involved in the pathobiology of PAH. A polymorphism in the serotonin transporter (SERT ...

The goal of the present study was to describe the molecular pharmacology of OPC-14597 ... as well as at novel serotonin receptor subtypes (5-HT 6 and 5-HT 7). Antagonism of dopamine-mediated ...