Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

Serine proteases are involved in an enormous number of biological processes (Stroud 1974). In every type of organism that scientists examine, they continue to discover new enzymes in this group.

The new study shows that "using serine as a therapy for Alzheimer's disease might not be the greatest idea," said Percy Griffin, director of scientific engagement for the Alzheimer's Association.

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor ...

Serine palmitoyltransferase (SPT) condenses serine and palmitoyl-CoA and is the rate-limiting enzyme in sphingolipid synthesis. 9 Variants in the genes SPTLC1 and SPTLC2, encoding two SPT subunits ...

Serine supports many biosynthetic pathways, including the one-carbon cycle. This Review discusses how cancer cells acquire and use serine, and explores novel therapeutic approaches to limit serine ...

Supplementation with amino acid serine eases neuropathy in diabetic mice Date: January 25, 2023 Source: Salk Institute Summary: The study adds to growing evidence that some often-underappreciated ...

Serine is currently being tested in clinical trials for its safety and efficacy in treating macular telangiectasia and Alzheimer’s disease. “… supplementation of serine and B vitamins ...

Serine is a nonessential amino acid, meaning the body produces it on its own and doesn’t need to get it from external food sources the way it does essential amino acids.

Adjunctive D-serine fails to outperform placebo in major depressive disorder but offers benefit in severe cases, especially along with higher-dose standard medications, a trial shows.