Overdiagnosis of sepsis and delayed optimization of antibiotics may reduce sepsis pathway effectiveness, according to researchers in Australia. “Although early antibiotic therapy is likely to reduce ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Philadelphia-based Penn Medicine is working to reduce sepsis readmissions and improve life after sepsis for survivors with a new post-discharge care pathway. Mark Mikkelsen, MD, chief of medical ...

Professors Yao Yongming and Du Xiaohui, leading a research group at the Chinese PLA General Hospital, have published groundbreaking findings demonstrating that CD4+ T lymphocytes undergo PANoptosis ...

Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Now, a new study finds that inhibition of a specific cell death pathway called "necroptosis" ...

A key immune response pathway regulated by zinc has been discovered by scientists that may hold clues to stopping sepsis, one of the leading causes of death in America’s intensive care units. As many ...

Death by sepsis is far from uncommon. A third of hospital deaths are caused by this complication of infections, which causes organ dysfunction. New research has identified a pathway that researchers ...

Sepsis, a deadly overreaction of the immune system to infection, has befuddled clinicians and researchers for decades. Covid-19 made things worse. The early signs and symptoms of sepsis mimic those of ...

Sepsis is the body's extreme response to an infection. It affects approximately 1.7 million adults in the United States each year and potentially contributes to more than 250,000 deaths. When ...